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A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis
The N-glycan of the IgG constant region (Fc) plays a central role in tuning and directing multiple antibody functions in vivo, including antibody-dependent cellular cytotoxicity, complement deposition, and the regulation of inflammation, among others. However, traditional methods of N-glycan analysi...
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| Veröffentlicht in: | J Immunol Methods |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5054724/ https://ncbi.nlm.nih.gov/pubmed/25523925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.12.004 |
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