Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination

Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the absence of neutralizing activity. Two modifications to the IgG constant domain (...

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Foilsithe in:PLoS Pathog
Main Authors: Mahan, Alison E., Jennewein, Madeleine F., Suscovich, Todd, Dionne, Kendall, Tedesco, Jacquelynne, Chung, Amy W., Streeck, Hendrik, Pau, Maria, Schuitemaker, Hanneke, Francis, Don, Fast, Patricia, Laufer, Dagna, Walker, Bruce D., Baden, Lindsey, Barouch, Dan H., Alter, Galit
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794126/
https://ncbi.nlm.nih.gov/pubmed/26982805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005456
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