Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement

HIV-specific broadly neutralizing antibodies (bNAbs) confer protection after passive immunization, but the immunological mechanisms that drive their development are poorly understood. Structural features of bNAbs indicate that they originate from extensive germinal center (GC) selection, which relie...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Lofano, Giuseppe, Gorman, Matthew J., Yousif, Ashraf S., Yu, Wen-Han, Fox, Julie M., Dugast, Anne-Sophie, Ackerman, Margaret E., Suscovich, Todd J., Weiner, Joshua, Barouch, Dan, Streeck, Hendrik, Little, Susan, Smith, Davey, Richman, Douglas, Lauffenburger, Douglas, Walker, Bruce D., Diamond, Michael S., Alter, Galit
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2018
Assuntos:
HIV
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298214/
https://ncbi.nlm.nih.gov/pubmed/30120121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aat7796
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados