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Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor
Angiotensin II type 1 receptor (AT(1)R) is the primary blood pressure regulator. AT(1)R blockers (ARBs) have been widely used in clinical settings as anti-hypertensive drugs and share a similar chemical scaffold, although even minor variations can lead to distinct therapeutic efficacies toward cardi...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705918/ https://ncbi.nlm.nih.gov/pubmed/26420482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.689000 |
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