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Divergent Spatiotemporal Interaction of Angiotensin Receptor Blocking Drugs with Angiotensin Type 1 Receptor

Crystal structures of the human angiotensin II type 1 receptor (AT(1)R) complex with the antihypertensive agent ZD7155 (PDB id: 4YAY) and the blood pressure medication Benicar (PDB id: 4ZUD) showed that binding poses of both antagonists are similar. This finding implies that clinically used angioten...

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Détails bibliographiques
Publié dans:J Chem Inf Model
Auteurs principaux: Dhanachandra Singh, Khuraijam, Unal, Hamiyet, Desnoyer, Russell, Karnik, Sadashiva S.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058968/
https://ncbi.nlm.nih.gov/pubmed/29195045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.7b00424
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