Divergent Spatiotemporal Interaction of Angiotensin Receptor Blocking Drugs with Angiotensin Type 1 Receptor

Crystal structures of the human angiotensin II type 1 receptor (AT(1)R) complex with the antihypertensive agent ZD7155 (PDB id: 4YAY) and the blood pressure medication Benicar (PDB id: 4ZUD) showed that binding poses of both antagonists are similar. This finding implies that clinically used angioten...

Full description

Saved in:
Bibliographic Details
Published in:J Chem Inf Model
Main Authors: Dhanachandra Singh, Khuraijam, Unal, Hamiyet, Desnoyer, Russell, Karnik, Sadashiva S.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058968/
https://ncbi.nlm.nih.gov/pubmed/29195045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.7b00424
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items