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Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase

BACKGROUND: The unique S28 family of proteases is comprised of the carboxypeptidase PRCP and the aminopeptidase DPP7. The structural basis of the different substrate specificities of the two enzymes is not understood nor has the structure of the S28 fold been described. RESULTS: The experimentally p...

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Detalhes bibliográficos
Main Authors: Soisson, Stephen M, Patel, Sangita B, Abeywickrema, Pravien D, Byrne, Noel J, Diehl, Ronald E, Hall, Dawn L, Ford, Rachael E, Reid, John C, Rickert, Keith W, Shipman, Jennifer M, Sharma, Sujata, Lumb, Kevin J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893456/
https://ncbi.nlm.nih.gov/pubmed/20540760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-10-16
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