Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase

BACKGROUND: The unique S28 family of proteases is comprised of the carboxypeptidase PRCP and the aminopeptidase DPP7. The structural basis of the different substrate specificities of the two enzymes is not understood nor has the structure of the S28 fold been described. RESULTS: The experimentally p...

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Autori principali: Soisson, Stephen M, Patel, Sangita B, Abeywickrema, Pravien D, Byrne, Noel J, Diehl, Ronald E, Hall, Dawn L, Ford, Rachael E, Reid, John C, Rickert, Keith W, Shipman, Jennifer M, Sharma, Sujata, Lumb, Kevin J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893456/
https://ncbi.nlm.nih.gov/pubmed/20540760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-10-16
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