Expression, purification and crystallization of human prolylcarboxypeptidase

Prolylcarboxypeptidase (PrCP) is a lysosomal serine carboxypeptidase that cleaves a variety of C-terminal amino acids adjacent to proline and has been implicated in diseases such as hypertension and obesity. Here, the robust production, purification and crystallization of glycosylated human PrCP fro...

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Detalhes bibliográficos
Main Authors: Abeywickrema, Pravien D., Patel, Sangita B., Byrne, Noel J., Diehl, Ronald E., Hall, Dawn L., Ford, Rachael E., Rickert, Keith W., Reid, John C., Shipman, Jennifer M., Geissler, Wayne M., Pryor, Kelly D., SinhaRoy, Ranabir, Soisson, Stephen M., Lumb, Kevin J., Sharma, Sujata
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Crystallization Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882774/
https://ncbi.nlm.nih.gov/pubmed/20516604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110014041
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