Expression, purification and crystallization of human prolylcarboxypeptidase

Prolylcarboxypeptidase (PrCP) is a lysosomal serine carboxypeptidase that cleaves a variety of C-terminal amino acids adjacent to proline and has been implicated in diseases such as hypertension and obesity. Here, the robust production, purification and crystallization of glycosylated human PrCP fro...

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Hlavní autoři: Abeywickrema, Pravien D., Patel, Sangita B., Byrne, Noel J., Diehl, Ronald E., Hall, Dawn L., Ford, Rachael E., Rickert, Keith W., Reid, John C., Shipman, Jennifer M., Geissler, Wayne M., Pryor, Kelly D., SinhaRoy, Ranabir, Soisson, Stephen M., Lumb, Kevin J., Sharma, Sujata
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2010
Témata:
Crystallization Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882774/
https://ncbi.nlm.nih.gov/pubmed/20516604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110014041
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