Expression, purification and crystallization of human prolylcarboxypeptidase

Prolylcarboxypeptidase (PrCP) is a lysosomal serine carboxypeptidase that cleaves a variety of C-terminal amino acids adjacent to proline and has been implicated in diseases such as hypertension and obesity. Here, the robust production, purification and crystallization of glycosylated human PrCP fro...

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Autori principali: Abeywickrema, Pravien D., Patel, Sangita B., Byrne, Noel J., Diehl, Ronald E., Hall, Dawn L., Ford, Rachael E., Rickert, Keith W., Reid, John C., Shipman, Jennifer M., Geissler, Wayne M., Pryor, Kelly D., SinhaRoy, Ranabir, Soisson, Stephen M., Lumb, Kevin J., Sharma, Sujata
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2010
Soggetti:
Crystallization Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882774/
https://ncbi.nlm.nih.gov/pubmed/20516604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110014041
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