Chromatin control of gene expression: Mixed-lineage leukemia methyltransferase SETs the stage for transcription

door Slany, Robert K.
Gepubliceerd in 2005

The molecular biology of mixed lineage leukemia

door Slany, Robert K.
Gepubliceerd in 2009

The Oncogenic Capacity of HRX-ENL Requires the Transcriptional Transactivation Activity of ENL and the DNA Binding Motifs of HRX

door Slany, Robert K., Lavau, Catherine, Cleary, Michael L.
Gepubliceerd in 1998

Direct Physical and Functional Interaction of the NuA4 Complex Components Yaf9p and Swc4p

door Bittner, Claudia B., Zeisig, Deniz T., Zeisig, Bernd B., Slany, Robert K.
Gepubliceerd in 2004

Pbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia

door Garcia-Cuellar, Maria-Paz, Steger, Julia, Füller, Elisa, Hetzner, Katrin, Slany, Robert K.
Gepubliceerd in Haematologica (2015)

The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

door Birke, Marco, Schreiner, Silke, García-Cuéllar, María-Paz, Mahr, Kerstin, Titgemeyer, Fritz, Slany, Robert K.
Gepubliceerd in 2002

Misguided Transcriptional Elongation Causes Mixed Lineage Leukemia

door Mueller, Dorothee, García-Cuéllar, María-Paz, Bach, Christian, Buhl, Sebastian, Maethner, Emanuel, Slany, Robert K.
Gepubliceerd in 2009

Exploitable metabolic dependencies in MLL-ENL–induced leukemia

door Garcia-Cuellar, Maria-Paz, Lawlor, Jennifer, Böttcher, Martin, Mougiakakos, Dimitrios, Metzler, Markus, Slany, Robert K.
Gepubliceerd in Blood Adv (2020)

Interaction of MLL Amino Terminal Sequences with Menin Is Required for Transformation

door Caslini, Corrado, Yang, Zhaohai, El-Osta, Mohamad, Milne, Thomas A., Slany, Robert K., Hess, Jay L.
Gepubliceerd in Cancer Res (2007)

Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL), a New Method to Detect Translocations in Leukemia

door Fueller, Elisa, Schaefer, Daniel, Fischer, Ute, Krell, Pina F. I., Stanulla, Martin, Borkhardt, Arndt, Slany, Robert K.
Gepubliceerd in 2014

HoxA9 transforms murine myeloid cells by a feedback loop driving expression of key oncogenes and cell cycle control genes

door Zhong, Xiaoxia, Prinz, Andreas, Steger, Julia, Garcia-Cuellar, Maria-Paz, Radsak, Markus, Bentaher, Abderrazzak, Slany, Robert K.
Gepubliceerd in Blood Adv (2018)

Meningioma 1 is indispensable for mixed lineage leukemia-rearranged acute myeloid leukemia

door Sharma, Amit, Jyotsana, Nidhi, Gabdoulline, Razif, Heckl, Dirk, Kuchenbauer, Florian, Slany, Robert K., Ganser, Arnold, Heuser, Michael
Gepubliceerd in Haematologica (2020)

MLL-ENL inhibits polycomb repressive complex 1 to achieve efficient transformation of hematopoietic cells

door Maethner, Emanuel, Garcia-Cuellar, Maria-Paz, Breitinger, Constanze, Takacova, Sylvia, Divoky, Vladimir, Hess, Jay L., Slany, Robert K.
Gepubliceerd in 2013

Myeloid transformation by MLL-ENL depends strictly on C/EBP

door Wesolowski, Radoslaw, Kowenz-Leutz, Elisabeth, Zimmermann, Karin, Dörr, Dorothea, Hofstätter, Maria, Slany, Robert K, Mildner, Alexander, Leutz, Achim
Gepubliceerd in Life Sci Alliance (2020)

c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells

door Hess, Jay L., Bittner, Claudia B., Zeisig, Deniz T., Bach, Christian, Fuchs, Uta, Borkhardt, Arndt, Frampton, Jon, Slany, Robert K.
Gepubliceerd in 2006

MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia

door Monroe, Sara C., Jo, Stephanie Y., Sanders, Daniel S., Basrur, Venkatesha, Elenitoba-Johnson, Kojo S., Slany, Robert K., Hess, Jay L.
Gepubliceerd in 2010

Retrovirus-Mediated Expression of E2A-PBX1 Blocks Lymphoid Fate but Permits Retention of Myeloid Potential in Early Hematopoietic Progenitors

door Woodcroft, Mark W., Nanan, Kyster, Thompson, Patrick, Tyryshkin, Kathrin, Smith, Steven P., Slany, Robert K., LeBrun, David P.
Gepubliceerd in PLoS One (2015)

A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification

door Mueller, Dorothee, Bach, Christian, Zeisig, Deniz, Garcia-Cuellar, Maria-Paz, Monroe, Sara, Sreekumar, Arun, Zhou, Rong, Nesvizhskii, Alexey, Chinnaiyan, Arul, Hess, Jay L., Slany, Robert K.
Gepubliceerd in 2007

Multiple Interferon Regulatory Factor and NF-κB Sites Cooperate in Mediating Cell-Type- and Maturation-Specific Activation of the Human CD83 Promoter in Dendritic Cells

door Stein, Marcello F., Lang, Stefan, Winkler, Thomas H., Deinzer, Andrea, Erber, Sebastian, Nettelbeck, Dirk M., Naschberger, Elisabeth, Jochmann, Ramona, Stürzl, Michael, Slany, Robert K., Werner, Thomas, Steinkasserer, Alexander, Knippertz, Ilka
Gepubliceerd in 2013

Hoxa9 and Meis1 Are Key Targets for MLL-ENL-Mediated Cellular Immortalization

door Zeisig, Bernd B., Milne, Tom, García-Cuéllar, María-Paz, Schreiner, Silke, Martin, Mary-Ellen, Fuchs, Uta, Borkhardt, Arndt, Chanda, Sumit K., Walker, John, Soden, Richard, Hess, Jay L., Slany, Robert K.
Gepubliceerd in 2004