MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia

OBJECTIVE: The aim of this study was to better understand how MLL fusion proteins deregulate the expression of genes critical for leukemia. MATERIALS AND METHODS: The transforming domain of one of the most common MLL fusion partners, AF9, was immuno-purified after expression in myeloblastic M1 cells...

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Hlavní autoři: Monroe, Sara C., Jo, Stephanie Y., Sanders, Daniel S., Basrur, Venkatesha, Elenitoba-Johnson, Kojo S., Slany, Robert K., Hess, Jay L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038424/
https://ncbi.nlm.nih.gov/pubmed/20854876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.09.003
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