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Heritable Genetic Background Alters Survival and Phenotype of Mll-AF9-Induced Leukemias

The MLL-AF9 fusion protein occurring as a result of t(9;11) translocation gives rise to pediatric and adult acute leukemias of distinct lineages, including acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and mixed phenotype acute leukemia (MPAL). The mechanisms underlying how this...

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Détails bibliographiques
Publié dans:Exp Hematol
Auteurs principaux: Young, Kira, Loberg, Matthew A., Eudy, Elizabeth, Schwartz, Logan S., Mujica, Kristina D., Trowbridge, Jennifer J.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508790/
https://ncbi.nlm.nih.gov/pubmed/32768438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2020.07.012
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