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MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia
OBJECTIVE: The aim of this study was to better understand how MLL fusion proteins deregulate the expression of genes critical for leukemia. MATERIALS AND METHODS: The transforming domain of one of the most common MLL fusion partners, AF9, was immuno-purified after expression in myeloblastic M1 cells...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038424/ https://ncbi.nlm.nih.gov/pubmed/20854876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.09.003 |
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