Exploitable metabolic dependencies in MLL-ENL–induced leukemia

Mixed-lineage leukemia (MLL) fusions are transcriptional activators that induce leukemia, with a dismal prognosis that mandates further elucidation of their transformation mechanism. In this study, knockdown of the direct MLL-ENL target gene polypyrimidine tract binding protein-1 (PTBP1) was rate li...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Garcia-Cuellar, Maria-Paz, Lawlor, Jennifer, Böttcher, Martin, Mougiakakos, Dimitrios, Metzler, Markus, Slany, Robert K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422118/
https://ncbi.nlm.nih.gov/pubmed/32766858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001710
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados