A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification

Chimeric proteins joining the histone methyltransferase MLL with various fusion partners trigger distinctive lymphoid and myeloid leukemias. Here, we immunopurified proteins associated with ENL, a protein commonly fused to MLL. Identification of these ENL-associated proteins (EAPs) by mass spectrome...

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Hlavní autoři: Mueller, Dorothee, Bach, Christian, Zeisig, Deniz, Garcia-Cuellar, Maria-Paz, Monroe, Sara, Sreekumar, Arun, Zhou, Rong, Nesvizhskii, Alexey, Chinnaiyan, Arul, Hess, Jay L., Slany, Robert K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2007
Témata:
Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234781/
https://ncbi.nlm.nih.gov/pubmed/17855633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-090514
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