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A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification

Chimeric proteins joining the histone methyltransferase MLL with various fusion partners trigger distinctive lymphoid and myeloid leukemias. Here, we immunopurified proteins associated with ENL, a protein commonly fused to MLL. Identification of these ENL-associated proteins (EAPs) by mass spectrome...

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Détails bibliographiques
Auteurs principaux: Mueller, Dorothee, Bach, Christian, Zeisig, Deniz, Garcia-Cuellar, Maria-Paz, Monroe, Sara, Sreekumar, Arun, Zhou, Rong, Nesvizhskii, Alexey, Chinnaiyan, Arul, Hess, Jay L., Slany, Robert K.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234781/
https://ncbi.nlm.nih.gov/pubmed/17855633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-090514
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