Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia

[Image: see text] Transcriptional coregulators, which mediate chromatin-dependent transcriptional signaling, represent tractable targets to modulate tumorigenic gene expression programs with small molecules. Genetic loss-of-function studies have recently implicated the transcriptional coactivator, E...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:ACS Cent Sci
Autores principales: Garnar-Wortzel, Leopold, Bishop, Timothy R., Kitamura, Seiya, Milosevich, Natalia, Asiaban, Joshua N., Zhang, Xiaoyu, Zheng, Qinheng, Chen, Emily, Ramos, Anissa R., Ackerman, Christopher J., Hampton, Eric N., Chatterjee, Arnab K., Young, Travis S., Hull, Mitchell V., Sharpless, K. Barry, Cravatt, Benjamin F., Wolan, Dennis W., Erb, Michael A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2021
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161486/
https://ncbi.nlm.nih.gov/pubmed/34079898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.0c01550
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares