The Oncogenic Capacity of HRX-ENL Requires the Transcriptional Transactivation Activity of ENL and the DNA Binding Motifs of HRX

The HRX gene (also called MLL, ALL-1, and Htrx) at chromosome band 11q23 is associated with specific subsets of acute leukemias through translocations that result in its fusion with a variety of heterologous partners. Two of these partners, ENL and AF9, code for proteins that are highly similar to e...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Slany, Robert K., Lavau, Catherine, Cleary, Michael L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Transcriptional Regulation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.122
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