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The Oncogenic Capacity of HRX-ENL Requires the Transcriptional Transactivation Activity of ENL and the DNA Binding Motifs of HRX

The HRX gene (also called MLL, ALL-1, and Htrx) at chromosome band 11q23 is associated with specific subsets of acute leukemias through translocations that result in its fusion with a variety of heterologous partners. Two of these partners, ENL and AF9, code for proteins that are highly similar to e...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Slany, Robert K., Lavau, Catherine, Cleary, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121463/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418860/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.122
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