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PU.1 can participate in an active enhancer complex without its transcriptional activation domain

The transcription factor PU.1 is necessary for the development of multiple hematopoietic lineages and contributes to the activity of the immunoglobulin κ 3′ enhancer. A variety of proteins bind to the 3′ enhancer (PU.1, PIP, ATF1, CREM, c-Fos, c-Jun, and E2A), but the mechanism of 3′-enhancer activi...

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Bibliografiska uppgifter
Huvudupphovsmän: Pongubala, Jagan M. R., Atchison, Michael L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC19254/
https://ncbi.nlm.nih.gov/pubmed/8990172
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