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Misguided Transcriptional Elongation Causes Mixed Lineage Leukemia
Fusion proteins composed of the histone methyltransferase mixed-lineage leukemia (MLL) and a variety of unrelated fusion partners are highly leukemogenic. Despite their prevalence, particularly in pediatric acute leukemia, many molecular details of their transforming mechanism are unknown. Here, we...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774266/ https://ncbi.nlm.nih.gov/pubmed/19956800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000249 |
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