Meningioma 1 is indispensable for mixed lineage leukemia-rearranged acute myeloid leukemia

Mixed lineage leukemia (MLL/KMT2A) rearrangements (MLL-r) are one of the most frequent chromosomal aberrations in acute myeloid leukemia. We evaluated the function of Meningioma 1 (MN1), a co-factor of HOXA9 and MEIS1, in human and murine MLL-rearranged leukemia by CRISPR-Cas9 mediated deletion of M...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Haematologica
Prif Awduron: Sharma, Amit, Jyotsana, Nidhi, Gabdoulline, Razif, Heckl, Dirk, Kuchenbauer, Florian, Slany, Robert K., Ganser, Arnold, Heuser, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ferrata Storti Foundation 2020
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193500/
https://ncbi.nlm.nih.gov/pubmed/31413090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.211201
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