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Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia

Hypomethylating agents are widely used in patients with myelodysplastic syndromes and unfit patients with acute myeloid leukemia. However, it is not well understood why only some patients respond to hypomethylating agents. We found previously that the effect of decitabine on hematopoietic stem cell...

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Bibliografiske detaljer
Udgivet i:Haematologica
Main Authors: Yun, Haiyang, Damm, Frederik, Yap, Damian, Schwarzer, Adrian, Chaturvedi, Anuhar, Jyotsana, Nidhi, Lübbert, Michael, Bullinger, Lars, Döhner, Konstanze, Geffers, Robert, Aparicio, Samuel, Humphries, R. Keith, Ganser, Arnold, Heuser, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562534/
https://ncbi.nlm.nih.gov/pubmed/24895338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.101386
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