Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL), a New Method to Detect Translocations in Leukemia

Here we present a novel method “Genomic inverse PCR for exploration of ligated breakpoints” (GIPFEL) that allows the sensitive detection of recurrent chromosomal translocations. This technique utilizes limited amounts of DNA as starting material and relies on PCR based quantification of unique DNA s...

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Main Authors: Fueller, Elisa, Schaefer, Daniel, Fischer, Ute, Krell, Pina F. I., Stanulla, Martin, Borkhardt, Arndt, Slany, Robert K.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138100/
https://ncbi.nlm.nih.gov/pubmed/25137060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104419
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