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Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL), a New Method to Detect Translocations in Leukemia

Here we present a novel method “Genomic inverse PCR for exploration of ligated breakpoints” (GIPFEL) that allows the sensitive detection of recurrent chromosomal translocations. This technique utilizes limited amounts of DNA as starting material and relies on PCR based quantification of unique DNA s...

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Hlavní autoři: Fueller, Elisa, Schaefer, Daniel, Fischer, Ute, Krell, Pina F. I., Stanulla, Martin, Borkhardt, Arndt, Slany, Robert K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138100/
https://ncbi.nlm.nih.gov/pubmed/25137060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104419
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