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Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL), a New Method to Detect Translocations in Leukemia

Here we present a novel method “Genomic inverse PCR for exploration of ligated breakpoints” (GIPFEL) that allows the sensitive detection of recurrent chromosomal translocations. This technique utilizes limited amounts of DNA as starting material and relies on PCR based quantification of unique DNA s...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Fueller, Elisa, Schaefer, Daniel, Fischer, Ute, Krell, Pina F. I., Stanulla, Martin, Borkhardt, Arndt, Slany, Robert K.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138100/
https://ncbi.nlm.nih.gov/pubmed/25137060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104419
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