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Insights into the prenatal origin of childhood acute lymphoblastic leukemia

Pediatric acute lymphoblastic leukemia (ALL) is defined by recurrent chromosomal aberrations including hyperdiploidy and chromosomal translocations. Many of these aberrations originate in utero and the cells transform in early childhood through acquired secondary mutations. In this review, we will d...

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Detalhes bibliográficos
Publicado no:Cancer Metastasis Rev
Main Authors: Hein, Daniel, Borkhardt, Arndt, Fischer, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098935/
https://ncbi.nlm.nih.gov/pubmed/31902036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-019-09841-1
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