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Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics
Many cancers have substantial genomic heterogeneity within a given tumor, and to fully understand that diversity requires the ability to perform single cell analysis. We performed targeted sequencing of a panel of single nucleotide variants (SNVs), deletions, and IgH sequences in 1,479 single tumor...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273416/ https://ncbi.nlm.nih.gov/pubmed/25425670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420822111 |
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