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GENOMIC ANALYSIS OF THE CLONAL ORIGINS OF RELAPSED ACUTE LYMPHOBLASTIC LEUKEMIA

Most children with acute lymphoblastic leukemia (ALL) can be cured, but for the subset of patients who undergo relapse prognosis is dismal. To explore the genetic basis of relapse, we performed genome-wide DNA copy number analyses on matched diagnosis and relapse samples from 61 patients with ALL. I...

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Detalhes bibliográficos
Main Authors: Mullighan, Charles G., Phillips, Letha A., Su, Xiaoping, Ma, Jing, Miller, Christopher B., Shurtleff, Sheila A., Downing, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746051/
https://ncbi.nlm.nih.gov/pubmed/19039135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164266
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