GENOMIC ANALYSIS OF THE CLONAL ORIGINS OF RELAPSED ACUTE LYMPHOBLASTIC LEUKEMIA

Por Mullighan, Charles G., Phillips, Letha A., Su, Xiaoping, Ma, Jing, Miller, Christopher B., Shurtleff, Sheila A., Downing, James R.
Publicado em 2008

Therapeutic In Vivo Selection of Thymic-Derived Natural T Regulatory Cells Following Non-Myeloablative Hematopoietic Stem Cell Transplant for IPEX

Por Kasow, Kimberly A., Morales-Tirado, Vanessa, Wichlan, David, Shurtleff, Sheila A., Abraham, Allistair, Persons, Derek A., Riberdy, Janice M.
Publicado em 2011

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells

Por Somervaille, Tim C. P., Matheny, Christina J., Spencer, Gary J., Iwasaki, Masayuki, Rinn, John L., Witten, Daniela M., Chang, Howard Y., Shurtleff, Sheila A., Downing, James R., Cleary, Michael L.
Publicado em 2009

MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas

Por Tatevossian, Ruth G., Tang, Bo, Dalton, James, Forshew, Tim, Lawson, Andrew R., Ma, Jing, Neale, Geoff, Shurtleff, Sheila A., Bailey, Simon, Gajjar, Amar, Baker, Suzanne J., Sheer, Denise, Ellison, David W.
Publicado em 2010

Replication-Competent Retroviruses in Gene-Modified T Cells Used in Clinical Trials: Is It Time to Revise the Testing Requirements?

Por Bear, Adham S, Morgan, Richard A, Cornetta, Kenneth, June, Carl H, Binder-Scholl, Gwendolyn, Dudley, Mark E, Feldman, Steven A, Rosenberg, Steven A, Shurtleff, Sheila A, Rooney, Cliona M, Heslop, Helen E, Dotti, Gianpietro
Publicado em 2012

Transcriptome profiling of patient derived xenograft models established from pediatric acute myeloid leukemia patients confirm maintenance of FLT3-ITD mutation

Por Drenberg, Christina D., Buelow, Daelynn R., Pounds, Stanley B., Wang, Yong-Dong, Finkelstein, David, Rahija, Richard J., Shurtleff, Sheila A., Rubnitz, Jeffrey E., Inaba, Hiroto, Gruber, Tanja A., Klco, Jeffery M., Baker, Sharyn D.
Publicado no Leuk Lymphoma (2016)

Phase I Pharmacokinetic and Pharmacodynamic Study of the Multikinase Inhibitor Sorafenib in Combination With Clofarabine and Cytarabine in Pediatric Relapsed/Refractory Leukemia

Por Inaba, Hiroto, Rubnitz, Jeffrey E., Coustan-Smith, Elaine, Li, Lie, Furmanski, Brian D., Mascara, Gerard P., Heym, Kenneth M., Christensen, Robbin, Onciu, Mihaela, Shurtleff, Sheila A., Pounds, Stanley B., Pui, Ching-Hon, Ribeiro, Raul C., Campana, Dario, Baker, Sharyn D.
Publicado em 2011

IMPACT OF TYROSINE KINASE INHIBITORS ON MINIMAL RESIDUAL DISEASE AND OUTCOME IN CHILDHOOD PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA

Por Jeha, Sima, Coustan-Smith, Elaine, Pei, Deqing, Sandlund, John T., Rubnitz, Jeffrey E., Howard, Scott C., Inaba, Hiroto, Bhojwani, Deepa, Metzger, Monika L., Cheng, Cheng, Choi, John K., Jacobsen, Jeffrey, Shurtleff, Sheila A., Raimondi, Susana, Ribeiro, Raul C., Pui, Ching-Hon, Campana, Dario
Publicado no Cancer (2014)

Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia

Por Radtke, Ina, Mullighan, Charles G., Ishii, Masami, Su, Xiaoping, Cheng, Jinjun, Ma, Jing, Ganti, Ramapriya, Cai, Zhongling, Goorha, Salil, Pounds, Stanley B., Cao, Xueyuan, Obert, Caroline, Armstrong, Jianling, Zhang, Jinghui, Song, Guangchun, Ribeiro, Raul C., Rubnitz, Jeffrey E., Raimondi, Susana C., Shurtleff, Sheila A., Downing, James R.
Publicado em 2009

IDH1 and IDH2 mutations in pediatric acute leukemia

Por Andersson, Anna K, Miller, David W, Lynch, John A, Lemoff, Andrew S, Cai, Zhongling, Pounds, Stanley B, Radtke, Ina, Yan, Bing, Schuetz, John D, Rubnitz, Jeffrey E, Ribeiro, Raul C, Raimondi, Susana C, Zhang, Jinghui, Mullighan, Charles G, Shurtleff, Sheila A, Schulman, Brenda A, Downing, James R
Publicado em 2011

Prognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy

Por Karol, Seth E, Coustan-Smith, Elaine, Cao, Xueyuan, Shurtleff, Sheila A, Raimondi, Susana C, Choi, John K, Ribeiro, Raul C, Dahl, Gary V, Bowman, W Paul, Taub, Jeffrey W, Degar, Barbara, Leung, Wing, Downing, James R, Pui, Ching-Hon, Rubnitz, Jeffrey E., Campana, Dario, Inaba, Hiroto
Publicado no Br J Haematol (2014)

Comparative Analysis of Different Approaches to Measure Treatment Response in Acute Myeloid Leukemia

Por Inaba, Hiroto, Coustan-Smith, Elaine, Cao, Xueyuan, Pounds, Stanley B., Shurtleff, Sheila A., Wang, Kathleen Y., Raimondi, Susana C., Onciu, Mihaela, Jacobsen, Jeffrey, Ribeiro, Raul C., Dahl, Gary V., Bowman, W. Paul, Taub, Jeffrey W., Degar, Barbara, Leung, Wing, Downing, James R., Pui, Ching-Hon, Rubnitz, Jeffrey E., Campana, Dario
Publicado em 2012

An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innovations in LEukemia study preph...

Por Kohlmann, Alexander, Kipps, Thomas J, Rassenti, Laura Z, Downing, James R, Shurtleff, Sheila A, Mills, Ken I, Gilkes, Amanda F, Hofmann, Wolf-Karsten, Basso, Giuseppe, Dell’Orto, Marta Campo, Foà, Robin, Chiaretti, Sabina, De Vos, John, Rauhut, Sonja, Papenhausen, Peter R, Hernández, Jesus M, Lumbreras, Eva, Yeoh, Allen E, Koay, Evelyn S, Li, Rachel, Liu, Wei-min, Williams, Paul M, Wieczorek, Lothar, Haferlach, Torsten
Publicado em 2008

Deletion of IKZF1 and Prognosis in Acute Lymphoblastic Leukemia

Por Mullighan, Charles G., Su, Xiaoping, Zhang, Jinghui, Radtke, Ina, Phillips, Letha A.A., Miller, Christopher B., Ma, Jing, Liu, Wei, Cheng, Cheng, Schulman, Brenda A., Harvey, Richard C., Chen, I-Ming, Clifford, Robert J., Carroll, William L., Reaman, Gregory, Bowman, W. Paul, Devidas, Meenakshi, Gerhard, Daniela S., Yang, Wenjian, Relling, Mary V., Shurtleff, Sheila A., Campana, Dario, Borowitz, Michael J., Pui, Ching-Hon, Smith, Malcolm, Hunger, Stephen P., Willman, Cheryl L., Downing, James R.
Publicado em 2009

Germline Mutations in Predisposition Genes in Pediatric Cancer

Por Zhang, Jinghui, Walsh, Michael F., Wu, Gang, Edmonson, Michael N., Gruber, Tanja A., Easton, John, Hedges, Dale, Ma, Xiaotu, Zhou, Xin, Yergeau, Donald A., Wilkinson, Mark R., Vadodaria, Bhavin, Chen, Xiang, McGee, Rose B., Hines-Dowell, Stacy, Nuccio, Regina, Quinn, Emily, Shurtleff, Sheila A., Rusch, Michael, Patel, Aman, Becksfort, Jared B., Wang, Shuoguo, Weaver, Meaghann S., Ding, Li, Mardis, Elaine R., Wilson, Richard K., Gajjar, Amar, Ellison, David W., Pappo, Alberto S., Pui, Ching-Hon, Nichols, Kim E., Downing, James R.
Publicado no N Engl J Med (2015)

The landscape of somatic mutations in epigenetic regulators across 1000 pediatric cancer genomes

Por Huether, Robert, Dong, Li, Chen, Xiang, Wu, Gang, Parker, Matthew, Wei, Lei, Ma, Jing, Edmonson, Michael N., Hedlund, Erin K., Rusch, Michael C., Shurtleff, Sheila A., Mulder, Heather L., Boggs, Kristy, Vadordaria, Bhavin, Cheng, Jinjun, Yergeau, Donald, Song, Guangchun, Becksfort, Jared, Lemmon, Gordon, Weber, Catherine, Cai, Zhongling, Dang, Jinjun, Walsh, Michael, Gedman, Amanda L., Faber, Zachary, Easton, John, Gruber, Tanja, Kriwacki, Richard W., Partridge, Janet F., Ding, Li, Wilson, Richard K., Mardis, Elaine R., Mullighan, Charles G., Gilbertson, Richard J., Baker, Suzanne J., Zambetti, Gerard, Ellison, David W., Zhang, Jinghui, Downing, James R.
Publicado em 2014

THE GENOMIC LANDSCAPE OF HYPODIPLOID ACUTE LYMPHOBLASTIC LEUKEMIA

Por Holmfeldt, Linda, Wei, Lei, Diaz-Flores, Ernesto, Walsh, Michael, Zhang, Jinghui, Ding, Li, Payne-Turner, Debbie, Churchman, Michelle, Andersson, Anna, Chen, Shann-Ching, McCastlain, Kelly, Becksfort, Jared, Ma, Jing, Wu, Gang, Patel, Samir N., Heatley, Susan L., Phillips, Letha A., Song, Guangchun, Easton, John, Parker, Matthew, Chen, Xiang, Rusch, Michael, Boggs, Kristy, Vadodaria, Bhavin, Hedlund, Erin, Drenberg, Christina, Baker, Sharyn, Pei, Deqing, Cheng, Cheng, Huether, Robert, Lu, Charles, Fulton, Robert S., Fulton, Lucinda L., Tabib, Yashodhan, Dooling, David J., Ochoa, Kerri, Minden, Mark, Lewis, Ian D., To, L. Bik, Marlton, Paula, Roberts, Andrew W., Raca, Gordana, Stock, Wendy, Neale, Geoffrey, Drexler, Hans G., Dickins, Ross A., Ellison, David W., Shurtleff, Sheila A., Pui, Ching-Hon, Ribeiro, Raul C., Devidas, Meenakshi, Carroll, Andrew J., Heerema, Nyla A., Wood, Brent, Borowitz, Michael J., Gastier-Foster, Julie M., Raimondi, Susana C., Mardis, Elaine R., Wilson, Richard K., Downing, James R., Hunger, Stephen P., Loh, Mignon L., Mullighan, Charles G.
Publicado em 2013

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Por Zhang, Jinghui, Ding, Li, Holmfeldt, Linda, Wu, Gang, Heatley, Sue L., Payne-Turner, Debbie, Easton, John, Chen, Xiang, Wang, Jianmin, Rusch, Michael, Lu, Charles, Chen, Shann-Ching, Wei, Lei, Collins-Underwood, J. Racquel, Ma, Jing, Roberts, Kathryn G., Pounds, Stanley B., Ulyanov, Anatoly, Becksfort, Jared, Gupta, Pankaj, Huether, Robert, Kriwacki, Richard W., Parker, Matthew, McGoldrick, Daniel J., Zhao, David, Alford, Daniel, Espy, Stephen, Bobba, Kiran Chand, Song, Guangchun, Pei, Deqing, Cheng, Cheng, Roberts, Stefan, Barbato, Michael I., Campana, Dario, Coustan-Smith, Elaine, Shurtleff, Sheila A., Raimondi, Susana C., Kleppe, Maria, Cools, Jan, Shimano, Kristin A., Hermiston, Michelle L., Doulatov, Sergei, Eppert, Kolja, Laurenti, Elisa, Notta, Faiyaz, Dick, John E., Basso, Giuseppe, Hunger, Stephen P., Loh, Mignon L., Devidas, Meenakshi, Wood, Brent, Winter, Stuart, Dunsmore, Kimberley P., Fulton, Robert S., Fulton, Lucinda L., Hong, Xin, Harris, Christopher C., Dooling, David J., Ochoa, Kerri, Johnson, Kimberly J., Obenauer, John C., Evans, William E., Pui, Ching-Hon, Naeve, Clayton W., Ley, Timothy J., Mardis, Elaine R., Wilson, Richard K., Downing, James R., Mullighan, Charles G.
Publicado em 2012

DEREGULATION OF DUX4 AND ERG IN ACUTE LYMPHOBLASTIC LEUKEMIA

Por Zhang, Jinghui, McCastlain, Kelly, Yoshihara, Hiroki, Xu, Beisi, Chang, Yunchao, Churchman, Michelle L., Wu, Gang, Li, Yongjin, Wei, Lei, Iacobucci, Ilaria, Liu, Yu, Qu, Chunxu, Wen, Ji, Edmonson, Michael, Payne-Turner, Debbie, Kaufmann, Kerstin B., Takayanagi, Shin-ichiro, Wienholds, Erno, Waanders, Esmé, Ntziachristos, Panagiotis, Bakogianni, Sofia, Wang, Jingjing, Aifantis, Iannis, Roberts, Kathryn G., Ma, Jing, Song, Guangchun, Easton, John, Mulder, Heather L., Chen, Xiang, Newman, Scott, Ma, Xiaotu, Rusch, Michael, Gupta, Pankaj, Boggs, Kristy, Vadodaria, Bhavin, Dalton, James, Liu, Yanling, Valentine, Marcus L, Ding, Li, Lu, Charles, Fulton, Robert S., Fulton, Lucinda, Tabib, Yashodhan, Ochoa, Kerri, Devidas, Meenakshi, Pei, Deqing, Cheng, Cheng, Yang, Jun, Evans, William E., Relling, Mary V., Pui, Ching-Hon, Jeha, Sima, Harvey, Richard C., Chen, I-Ming L, Willman, Cheryl L., Marcucci, Guido, Bloomfield, Clara D., Kohlschmidt, Jessica, Mrózek, Krzysztof, Paietta, Elisabeth, Tallman, Martin S., Stock, Wendy, Foster, Matthew C., Racevskis, Janis, Rowe, Jacob M., Luger, Selina, Kornblau, Steven M., Shurtleff, Sheila A, Raimondi, Susana C., Mardis, Elaine R., Wilson, Richard K., Dick, John E., Hunger, Stephen P, Loh, Mignon L., Downing, James R., Mullighan, Charles G.
Publicado no Nat Genet (2016)