Therapeutic In Vivo Selection of Thymic-Derived Natural T Regulatory Cells Following Non-Myeloablative Hematopoietic Stem Cell Transplant for IPEX

FOXP3 is critical for the development and function of CD4(+)CD25(bright) natural regulatory T cells (nTreg). Individuals harboring mutations in FOXP3 develop immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX). We describe a child diagnosed with IPEX who underwent a reduc...

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Detalhes bibliográficos
Main Authors: Kasow, Kimberly A., Morales-Tirado, Vanessa, Wichlan, David, Shurtleff, Sheila A., Abraham, Allistair, Persons, Derek A., Riberdy, Janice M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200481/
https://ncbi.nlm.nih.gov/pubmed/21865090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2011.07.005
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