Increased Engraftment of Human Short Term Repopulating Hematopoietic Cells in NOD/SCID/IL2rγ(null) Mice by Lentiviral Expression of NUP98-HOXA10HD

Techniques to expand human hematopoietic stem cells ex-vivo could be beneficial to the fields of clinical hematopoietic stem cell transplantation and gene therapy targeted at hematopoietic stem cells. NUP98-HOXA10HD is a relatively newly discovered fusion gene that in mouse transplant experiments ha...

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Veröffentlicht in:PLoS One
Hauptverfasser: Abraham, Allistair, Kim, Yoon-Sang, Zhao, Huifen, Humphries, Keith, Persons, Derek A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711970/
https://ncbi.nlm.nih.gov/pubmed/26761813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147059
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