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IMPACT OF TYROSINE KINASE INHIBITORS ON MINIMAL RESIDUAL DISEASE AND OUTCOME IN CHILDHOOD PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA

BACKGROUND: BCR-ABL1 tyrosine kinase inhibitors (TKIs) improve the outcome of childhood Philadelphia-chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) when incorporated into post-remission induction chemotherapy. No data is available on the impact of TKIs on end of induction minimal residua...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Jeha, Sima, Coustan-Smith, Elaine, Pei, Deqing, Sandlund, John T., Rubnitz, Jeffrey E., Howard, Scott C., Inaba, Hiroto, Bhojwani, Deepa, Metzger, Monika L., Cheng, Cheng, Choi, John K., Jacobsen, Jeffrey, Shurtleff, Sheila A., Raimondi, Susana, Ribeiro, Raul C., Pui, Ching-Hon, Campana, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249731/
https://ncbi.nlm.nih.gov/pubmed/24501014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28598
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