IMPACT OF TYROSINE KINASE INHIBITORS ON MINIMAL RESIDUAL DISEASE AND OUTCOME IN CHILDHOOD PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA

BACKGROUND: BCR-ABL1 tyrosine kinase inhibitors (TKIs) improve the outcome of childhood Philadelphia-chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) when incorporated into post-remission induction chemotherapy. No data is available on the impact of TKIs on end of induction minimal residua...

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Publicat a:Cancer
Autors principals: Jeha, Sima, Coustan-Smith, Elaine, Pei, Deqing, Sandlund, John T., Rubnitz, Jeffrey E., Howard, Scott C., Inaba, Hiroto, Bhojwani, Deepa, Metzger, Monika L., Cheng, Cheng, Choi, John K., Jacobsen, Jeffrey, Shurtleff, Sheila A., Raimondi, Susana, Ribeiro, Raul C., Pui, Ching-Hon, Campana, Dario
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249731/
https://ncbi.nlm.nih.gov/pubmed/24501014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28598
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