ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy

ETV6-RUNX1 fusion is the most common genetic aberration in childhood acute lymphoblastic leukemia (ALL). To evaluate whether outcomes for this drug-sensitive leukemia are improved by contemporary risk-directed therapy, we studied clinical features, response and adverse events of 168 children with ne...

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Main Authors: Bhojwani, Deepa, Pei, Deqing, Sandlund, John T., Jeha, Sima, Ribeiro, Raul C., Rubnitz, Jeffrey E., Raimondi, Susana C., Shurtleff, Sheila, Onciu, Mihaela, Cheng, Cheng, Coustan-Smith, Elaine, Bowman, W. Paul, Howard, Scott C., Metzger, Monika L., Inaba, Hiroto, Leung, Wing, Evans, William E., Campana, Dario, Relling, Mary V., Pui, Ching-Hon
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345278/
https://ncbi.nlm.nih.gov/pubmed/21869842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.227
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