Clinical Utility of Sequential Minimal Residual Disease Measurements in the Context of Risk-based Therapy in Childhood Acute Lymphoblastic Leukemia: a Prospective Study

BACKGROUND: The level of minimal residual disease (MRD) during remission induction is the most important prognostic indicator in acute lymphoblastic leukemia (ALL). We determined the clinical significance of MRD in the context of a prospective clinical study in which sequential MRD measurements were...

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Udgivet i:Lancet Oncol
Main Authors: Pui, Ching-Hon, Pei, Deqing, Coustan-Smith, Elaine, Jeha, Sima, Cheng, Cheng, Bowman, W Paul, Sandlund, John T, Ribeiro, Raul C, Rubnitz, Jeffrey E, Inaba, Hiroto, Bhojwani, Deepa, Gruber, Tanja A, Leung, Wing H, Downing, James R, Evans, William E, Relling, Mary V, Campana, Dario
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612585/
https://ncbi.nlm.nih.gov/pubmed/25800893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(15)70082-3
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