Clinical Utility of Sequential Minimal Residual Disease Measurements in the Context of Risk-based Therapy in Childhood Acute Lymphoblastic Leukemia: a Prospective Study

BACKGROUND: The level of minimal residual disease (MRD) during remission induction is the most important prognostic indicator in acute lymphoblastic leukemia (ALL). We determined the clinical significance of MRD in the context of a prospective clinical study in which sequential MRD measurements were...

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Publicado en:Lancet Oncol
Autores principales: Pui, Ching-Hon, Pei, Deqing, Coustan-Smith, Elaine, Jeha, Sima, Cheng, Cheng, Bowman, W Paul, Sandlund, John T, Ribeiro, Raul C, Rubnitz, Jeffrey E, Inaba, Hiroto, Bhojwani, Deepa, Gruber, Tanja A, Leung, Wing H, Downing, James R, Evans, William E, Relling, Mary V, Campana, Dario
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612585/
https://ncbi.nlm.nih.gov/pubmed/25800893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(15)70082-3
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