Mutational Landscape and Patterns of Clonal Evolution in Relapsed Pediatric Acute Lymphoblastic Leukemia

Relapse of acute lymphoblastic leukemia (ALL) remains a leading cause of childhood cancer-related death. Prior studies have shown clonal mutations at relapse often arise from relapse-fated subclones that exist at diagnosis. However, the genomic landscape, evolutionary trajectories, and mutational me...

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發表在:Blood Cancer Discov
Main Authors: Waanders, Esmé, Gu, Zhaohui, Dobson, Stephanie M., Antić, Željko, Crawford, Jeremy Chase, Ma, Xiaotu, Edmonson, Michael N., Payne-Turner, Debbie, van de Vorst, Maartje, Jongmans, Marjolijn C.J., McGuire, Irina, Zhou, Xin, Wang, Jian, Shi, Lei, Pounds, Stanley, Pei, Deqing, Cheng, Cheng, Song, Guangchun, Fan, Yiping, Shao, Ying, Rusch, Michael, McCastlain, Kelly, Yu, Jiangyan, van Boxtel, Ruben, Blokzijl, Francis, Iacobucci, Ilaria, Roberts, Kathryn G., Wen, Ji, Wu, Gang, Ma, Jing, Easton, John, Neale, Geoffrey, Olsen, Scott R., Nichols, Kim E., Pui, Ching-Hon, Zhang, Jinghui, Evans, William E., Relling, Mary V., Yang, Jun J., Thomas, Paul G., Dick, John E., Kuiper, Roland P., Mullighan, Charles G.
格式: Artigo
語言:Inglês
出版: American Association for Cancer Research 2020
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418874/
https://ncbi.nlm.nih.gov/pubmed/32793890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.BCD-19-0041
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