Llwytho...
Pbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia
Hox homeobox transcription factors drive leukemogenesis efficiently only in the presence of Meis or Pbx proteins. Here we show that Pbx3 and Meis1 need to dimerize to support Hox-induced leukemia and we analyze the molecular details of this cooperation. In the absence of Pbx3, Meis1 was highly unsta...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Haematologica |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Ferrata Storti Foundation
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4486225/ https://ncbi.nlm.nih.gov/pubmed/25911551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.124032 |
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