Drug repurposing and human parasitic protozoan diseases

Por Andrews, Katherine T., Fisher, Gillian, Skinner-Adams, Tina S.
Publicado em 2014

Comparison of Plasmodium falciparum transfection methods

Por Skinner-Adams, Tina S, Lawrie, Paula M, Hawthorne, Paula L, Gardiner, Donald L, Trenholme, Katharine R
Publicado em 2003

Saquinavir Inhibits the Malaria Parasite's Chloroquine Resistance Transporter

Por Martin, Rowena E., Butterworth, Alice S., Gardiner, Donald L., Kirk, Kiaran, McCarthy, James S., Skinner-Adams, Tina S.
Publicado em 2012

A novel in vitro image-based assay identifies new drug leads for giardiasis

Por Hart, Christopher J.S., Munro, Taylah, Andrews, Katherine T., Ryan, John H., Riches, Andrew G., Skinner-Adams, Tina S.
Publicado no Int J Parasitol Drugs Drug Resist (2017)

Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A–D

Por Schwartz, Brett D., Coster, Mark J., Skinner-Adams, Tina S., Andrews, Katherine T., White, Jonathan M., Davis, Rohan A.
Publicado no Mar Drugs (2015)

Adaptation of the [(3)H]Hypoxanthine Uptake Assay for In Vitro-Cultured Plasmodium knowlesi Malaria Parasites

Por Arnold, Megan S. J., Engel, Jessica A., Chua, Ming Jang, Fisher, Gillian M., Skinner-Adams, Tina S., Andrews, Katherine T.
Publicado no Antimicrob Agents Chemother (2016)

Erratum to “Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites” [Int. J. Parasitol. Drugs Drug Res. 5 (2015) 117–126]...

Por Engel, Jessica A., Jones, Amy J., Avery, Vicky M., Sumanadasa, Subathdrage D.M., Ng, Susanna S., Fairlie, David P., Skinner-Adams, Tina, Andrews, Katherine T.
Publicado no Int J Parasitol Drugs Drug Resist (2016)

Antimalarial Asexual Stage-Specific and Gametocytocidal Activities of HIV Protease Inhibitors

Por Peatey, Christopher L., Andrews, Katherine T., Eickel, Nina, MacDonald, Timothy, Butterworth, Alice S., Trenholme, Katharine R., Gardiner, Donald L., McCarthy, James S., Skinner-Adams, Tina S.
Publicado em 2010

Fingerprinting the Substrate Specificity of M1 and M17 Aminopeptidases of Human Malaria, Plasmodium falciparum

Por Poreba, Marcin, McGowan, Sheena, Skinner-Adams, Tina S., Trenholme, Katharine R., Gardiner, Donald L., Whisstock, James C., To, Joyce, Salvesen, Guy S., Dalton, John P., Drag, Marcin
Publicado em 2012

Antimalarial Activity of the Anticancer Histone Deacetylase Inhibitor SB939

Por Sumanadasa, Subathdrage D. M., Goodman, Christopher D., Lucke, Andrew J., Skinner-Adams, Tina, Sahama, Ishani, Haque, Ashraful, Do, Tram Anh, McFadden, Geoffrey I., Fairlie, David P., Andrews, Katherine T.
Publicado em 2012

Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth

Por Chua, Ming Jang, Arnold, Megan S.J., Xu, Weijun, Lancelot, Julien, Lamotte, Suzanne, Späth, Gerald F., Prina, Eric, Pierce, Raymond J., Fairlie, David P., Skinner-Adams, Tina S., Andrews, Katherine T.
Publicado no Int J Parasitol Drugs Drug Resist (2016)

The Aminopeptidase Inhibitor CHR-2863 Is an Orally Bioavailable Inhibitor of Murine Malaria

Por Skinner-Adams, Tina S., Peatey, Christopher L., Anderson, Karen, Trenholme, Katharine R., Krige, David, Brown, Christopher L., Stack, Colin, Nsangou, Desire M. M., Mathews, Rency T., Thivierge, Karine, Dalton, John P., Gardiner, Donald L.
Publicado em 2012

Potencies of Human Immunodeficiency Virus Protease Inhibitors In Vitro against Plasmodium falciparum and In Vivo against Murine Malaria

Por Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin, McCarthy, James S.
Publicado em 2006

Total Synthesis of Thiaplakortone A: Derivatives as Metabolically Stable Leads for the Treatment of Malaria

Por Pouwer, Rebecca H., Deydier, Sophie M., Le, Phuc Van, Schwartz, Brett D., Franken, Nicole C., Davis, Rohan A., Coster, Mark J., Charman, Susan A., Edstein, Michael D., Skinner-Adams, Tina S., Andrews, Katherine T., Jenkins, Ian D., Quinn, Ronald J.
Publicado em 2013

The Frequency of Malaria Is Similar among Women Receiving either Lopinavir/Ritonavir or Nevirapine-based Antiretroviral Treatment

Por Skinner-Adams, Tina S., Butterworth, Alice S., Porter, Kimberly A., D'Amico, Ronald, Sawe, Fred, Shaffer, Doug, Siika, Abraham, Hosseinipour, Mina C., Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, Lockman, Shahin, Eron, Joseph J., Meshnick, Steven R., McCarthy, James S.
Publicado em 2012

Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases

Por McGowan, Sheena, Oellig, Christine A., Birru, Woldeamanuel A., Caradoc-Davies, Tom T., Stack, Colin M., Lowther, Jonathan, Skinner-Adams, Tina, Mucha, Artur, Kafarski, Pawel, Grembecka, Jolanta, Trenholme, Katharine R., Buckle, Ashley M., Gardiner, Donald L., Dalton, John P., Whisstock, James C.
Publicado em 2010

Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules

Por Trenholme, Katharine, Marek, Linda, Duffy, Sandra, Pradel, Gabriele, Fisher, Gillian, Hansen, Finn K., Skinner-Adams, Tina S., Butterworth, Alice, Ngwa, Che Julius, Moecking, Jonas, Goodman, Christopher D., McFadden, Geoffrey I., Sumanadasa, Subathdrage D. M., Fairlie, David P., Avery, Vicky M., Kurz, Thomas, Andrews, Katherine T.
Publicado em 2014

Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High Throughput Screening

Por Spicer, Timothy, Fernandez-Vega, Virneliz, Chase, Peter, Scampavia, Louis, To, Joyce, Dalton, John P, Da Silva, Fabio L, Skinner-Adams, Tina S, Gardiner, Donald L, Trenholme, Katharine R, Brown, Christopher L, Ghosh, Partha, Porubsky, Patrick, Wang, Jenna L, Whipple, David A, Schoenen, Frank J, Hodder, Peter
Publicado no J Biomol Screen (2014)

Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase

Por McGowan, Sheena, Porter, Corrine J., Lowther, Jonathan, Stack, Colin M., Golding, Sarah J., Skinner-Adams, Tina S., Trenholme, Katharine R., Teuscher, Franka, Donnelly, Sheila M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, DeGori, Ross, Buckle, Ashley M., Gardiner, Donald L., Whisstock, James C., Dalton, John P.
Publicado em 2009

HIV-1 Protease Inhibitors and Clinical Malaria: a Secondary Analysis of the AIDS Clinical Trials Group A5208 Study

Por Porter, Kimberly A., Cole, Stephen R., Eron, Joseph J., Zheng, Yu, Hughes, Michael D., Lockman, Shahin, Poole, Charles, Skinner-Adams, Tina S., Hosseinipour, Mina, Shaffer, Doug, D'Amico, Ronald, Sawe, Frederick K., Siika, Abraham, Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, McCarthy, James S., Meshnick, Steven R.
Publicado em 2012