Antimalarial Asexual Stage-Specific and Gametocytocidal Activities of HIV Protease Inhibitors

The stage-specific antimalarial activities of a panel of antiretroviral protease inhibitors (PIs), including two nonpeptidic PIs (tipranavir and darunavir), were tested in vitro against Plasmodium falciparum. While darunavir demonstrated limited antimalarial activity (effective concentration [EC(50)...

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Detalhes bibliográficos
Main Authors: Peatey, Christopher L., Andrews, Katherine T., Eickel, Nina, MacDonald, Timothy, Butterworth, Alice S., Trenholme, Katharine R., Gardiner, Donald L., McCarthy, James S., Skinner-Adams, Tina S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825985/
https://ncbi.nlm.nih.gov/pubmed/20028821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01512-09
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