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Synergistic Interactions of the Antiretroviral Protease Inhibitors Saquinavir and Ritonavir with Chloroquine and Mefloquine against Plasmodium falciparum In Vitro

The antimalarial activity of several antiretroviral protease inhibitor combinations was investigated. Data demonstrate that ritonavir and saquinavir behave synergistically with chloroquine and mefloquine. These data, and interactions with pepstatin-A, E-64, and bestatin, suggest that human immunodef...

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Detalhes bibliográficos
Main Authors: Skinner-Adams, T. S., Andrews, K. T., Melville, L., McCarthy, J., Gardiner, D. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797772/
https://ncbi.nlm.nih.gov/pubmed/17088482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00840-06
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