An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation

por Hesping, Eva, Skinner-Adams, Tina S., Fisher, Gillian M., Kurz, Thomas, Andrews, Katherine T.
Publicado en Int J Parasitol Drugs Drug Resist (2020)

Crystal Structure of Brucella abortus Deoxyxylulose-5-phosphate Reductoisomerase-like (DRL) Enzyme Involved in Isoprenoid Biosynthesis

por Pérez-Gil, Jordi, Calisto, Bárbara M., Behrendt, Christoph, Kurz, Thomas, Fita, Ignacio, Rodríguez-Concepción, Manuel
Publicado 2012

Priming with HDAC Inhibitors Sensitizes Ovarian Cancer Cells to Treatment with Cisplatin and HSP90 Inhibitors

por Rodrigues Moita, Ana J., Bandolik, Jan J., Hansen, Finn K., Kurz, Thomas, Hamacher, Alexandra, Kassack, Matthias U.
Publicado en Int J Mol Sci (2020)

TRTH-28. HIGH THROUGHPUT SCREENING OF NOVEL HISTONE DEACETYLASE INHIBITORS FOR EPIGENETIC THERAPY OF PRIMARY BRAIN TUMORS

por Marquardt, Viktoria, Pauck, David, Hansen, Finn K., Picard, Daniel, Felsberg, Jörg, Reifenberger, Guido, Borkhardt, Arndt, Kurz, Thomas, Remke, Marc
Publicado en Neuro Oncol (2017)

Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity

por Porter, Nicholas J., Osko, Jeremy D., Diedrich, Daniela, Kurz, Thomas, Hooker, Jacob M., Hansen, Finn K., Christianson, David W.
Publicado en J Med Chem (2018)

Application of Histone Deacetylase Inhibitors MPK472 and KSK64 as a Potential Treatment Option for Acanthamoeba Keratitis

por Lee, Hae-Ahm, Park, So-Min, Chu, Ki-Back, Quan, Fu-Shi, Kurz, Thomas, Pflieger, Marc, Moon, Eun-Kyung
Publicado en Antimicrob Agents Chemother (2020)

IMMU-19. HDAC INHIBITORS SENSITIZE MYC-AMPLIFIED MEDULLOBLASTOMA TO IMMUNOTHERAPY BY ACTIVATING THE NF-kB PATHWAYS

por Marquardt, Viktoria, Theruvath, Johanna, Pauck, David, Picard, Daniel, Reifenberger, Guido, Borkhardt, Arndt, Cheshier, Samuel, Kurz, Thomas, Remke, Marc, Mitra, Siddhartha
Publicado en Neuro Oncol (2020)

Design, synthesis and biological evaluation of β-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity

por Reßing, Nina, Marquardt, Viktoria, Gertzen, Christoph G. W., Schöler, Andrea, Schramm, Alexander, Kurz, Thomas, Gohlke, Holger, Aigner, Achim, Remke, Marc, Hansen, Finn K.
Publicado en Medchemcomm (2018)

Cell Type-Dependent Escape of Capsid Inhibitors by Simian Immunodeficiency Virus SIVcpz

por Twizerimana, Augustin Penda, Scheck, Rachel, Becker, Daniel, Zhang, Zeli, Wammers, Marianne, Avelar, Leandro, Pflieger, Marc, Häussinger, Dieter, Kurz, Thomas, Gohlke, Holger, Münk, Carsten
Publicado en J Virol (2020)

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation

por Franzke, Claus-Werner, Cobzaru, Cristina, Triantafyllopoulou, Antigoni, Löffek, Stefanie, Horiuchi, Keisuke, Threadgill, David W., Kurz, Thomas, van Rooijen, Nico, Bruckner-Tuderman, Leena, Blobel, Carl P.
Publicado 2012

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

por Franzke, Claus-Werner, Cobzaru, Cristina, Triantafyllopoulou, Antigoni, Löffek, Stefanie, Horiuchi, Keisuke, Threadgill, David W., Kurz, Thomas, van Rooijen, Nico, Bruckner-Tuderman, Leena, Blobel, Carl P.
Publicado 2012

Discovery of the first-in-class dual histone deacetylase-proteasome inhibitor

por Bhatia, Sanil, Krieger, Viktoria, Groll, Michael, Osko, Jeremy D., Reßing, Nina, Ahlert, Heinz, Borkhardt, Arndt, Kurz, Thomas, Christianson, David W., Hauer, Julia, Hansen, Finn K.
Publicado en J Med Chem (2018)

Class I HDACs specifically regulate E‐cadherin expression in human renal epithelial cells

por Choi, Sin Y., Kee, Hae J., Kurz, Thomas, Hansen, Finn K., Ryu, Yuhee, Kim, Gwi R., Lin, Ming Q., Jin, Li, Piao, Zhe H., Jeong, Myung H.
Publicado en J Cell Mol Med (2016)

MBRS-16. HDAC AND NFκB ANTAGONISTS SYNERGISTICALLY INHIBIT GROWTH OF MYC-DRIVEN MEDULLOBLASTOMA

por Marquardt, Viktoria, Theruvath, Johanna, Pauck, David, Picard, Daniel, Qin, Nan, Blümel, Lena, Hansen, Finn, Felsberg, Jörg, Cheshier, Samuel, Reifenberger, Guido, Borkhardt, Arndt, Kurz, Thomas, Mitra, Siddhartha, Remke, Marc
Publicado en Neuro Oncol (2018)

Phenotypic screening of the ‘Kurz-box’ of chemicals identifies two compounds (BLK127 and HBK4) with anthelmintic activity in vitro against parasitic larval stages of Haemonchus con...

por Nguyen, Linh Thuy, Kurz, Thomas, Preston, Sarah, Brueckmann, Hjoerdis, Lungerich, Beate, Herath, H. M. P. Dilrukshi, Koehler, Anson V., Wang, Tao, Skálová, Lenka, Jabbar, Abdul, Gasser, Robin B.
Publicado en Parasit Vectors (2019)

In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi)

por Friedrich, Annabelle, Assmann, Ann-Sophie, Schumacher, Lena, Stuijvenberg, Jana v., Kassack, Matthias U., Schulz, Wolfgang A., Roos, Wynand P., Hansen, Finn K., Pflieger, Marc, Kurz, Thomas, Fritz, Gerhard
Publicado en Int J Mol Sci (2020)

Oxa Analogues of Nexturastat A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity

por Pflieger, Marc, Sönnichsen, Melf, Horstick‐Muche, Nadine, Yang, Jing, Schliehe‐Diecks, Julian, Schöler, Andrea, Borkhardt, Arndt, Hamacher, Alexandra, Kassack, Matthias U., Hansen, Finn K., Bhatia, Sanil, Kurz, Thomas
Publicado en ChemMedChem (2021)

Class I histone deacetylase inhibitor MS-275 attenuates vasoconstriction and inflammation in angiotensin II-induced hypertension

por Ryu, Yuhee, Kee, Hae Jin, Sun, Simei, Seok, Young Mi, Choi, Sin Young, Kim, Gwi Ran, Kee, Seung-Jung, Pflieger, Marc, Kurz, Thomas, Kim, Hyung-Seok, Jeong, Myung Ho
Publicado en PLoS One (2019)

Histone deacetylase inhibitor LMK235 attenuates vascular constriction and aortic remodelling in hypertension

por Choi, Sin Young, Kee, Hae Jin, Sun, Simei, Seok, Young Mi, Ryu, Yuhee, Kim, Gwi Ran, Kee, Seung‐Jung, Pflieger, Marc, Kurz, Thomas, Kassack, Matthias U., Jeong, Myung Ho
Publicado en J Cell Mol Med (2019)

MEDU-20. HDAC AND NFκB ANTAGONISTS SYNERGISTICALLY INHIBIT GROWTH OF MYC-DRIVEN MEDULLOBLASTOMA

por Marquardt, Viktoria, Theruvath, Johanna, Pauck, David, Picard, Daniel, Qin, Nan, Blümel, Lena, Hansen, Finn K, Felsberg, Jörg, Cheshier, Samuel, Reifenberger, Guido, Borkhardt, Arndt, Kurz, Thomas, Mitra, Siddhartha, Remke, Marc
Publicado en Neuro Oncol (2019)