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MEDU-20. HDAC AND NFκB ANTAGONISTS SYNERGISTICALLY INHIBIT GROWTH OF MYC-DRIVEN MEDULLOBLASTOMA

Medulloblastoma is the most common malignant brain tumor in childhood and comprises four distinct molecular subgroups with further layers of intertumoral heterogeneity. Amplification of the oncogene MYC drives tumorigenesis and constitutes a hallmark feature underlying Group 3 biology. Metastatic di...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Marquardt, Viktoria, Theruvath, Johanna, Pauck, David, Picard, Daniel, Qin, Nan, Blümel, Lena, Hansen, Finn K, Felsberg, Jörg, Cheshier, Samuel, Reifenberger, Guido, Borkhardt, Arndt, Kurz, Thomas, Mitra, Siddhartha, Remke, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477330/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.179
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