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MEDU-20. HDAC AND NFκB ANTAGONISTS SYNERGISTICALLY INHIBIT GROWTH OF MYC-DRIVEN MEDULLOBLASTOMA

Medulloblastoma is the most common malignant brain tumor in childhood and comprises four distinct molecular subgroups with further layers of intertumoral heterogeneity. Amplification of the oncogene MYC drives tumorigenesis and constitutes a hallmark feature underlying Group 3 biology. Metastatic di...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Marquardt, Viktoria, Theruvath, Johanna, Pauck, David, Picard, Daniel, Qin, Nan, Blümel, Lena, Hansen, Finn K, Felsberg, Jörg, Cheshier, Samuel, Reifenberger, Guido, Borkhardt, Arndt, Kurz, Thomas, Mitra, Siddhartha, Remke, Marc
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477330/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.179
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