MEDU-20. HDAC AND NFκB ANTAGONISTS SYNERGISTICALLY INHIBIT GROWTH OF MYC-DRIVEN MEDULLOBLASTOMA

Medulloblastoma is the most common malignant brain tumor in childhood and comprises four distinct molecular subgroups with further layers of intertumoral heterogeneity. Amplification of the oncogene MYC drives tumorigenesis and constitutes a hallmark feature underlying Group 3 biology. Metastatic di...

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Enregistré dans:
Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Marquardt, Viktoria, Theruvath, Johanna, Pauck, David, Picard, Daniel, Qin, Nan, Blümel, Lena, Hansen, Finn K, Felsberg, Jörg, Cheshier, Samuel, Reifenberger, Guido, Borkhardt, Arndt, Kurz, Thomas, Mitra, Siddhartha, Remke, Marc
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Medulloblastoma
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477330/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.179
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