A Membrane-proximal, C-terminal α-Helix Is Required for Plasma Membrane Localization and Function of the G Protein-coupled Receptor (GPCR) TGR5

Por Spomer, Lina, Gertzen, Christoph G. W., Schmitz, Birte, Häussinger, Dieter, Gohlke, Holger, Keitel, Verena
Publicado em 2014

Identification of a Conserved Interface of Human Immunodeficiency Virus Type 1 and Feline Immunodeficiency Virus Vifs with Cullin 5

Por Gu, Qinyong, Zhang, Zeli, Gertzen, Christoph G. W., Häussinger, Dieter, Gohlke, Holger, Münk, Carsten
Publicado no J Virol (2018)

Interaction of Ochratoxin A and Its Thermal Degradation Product 2′R-Ochratoxin A with Human Serum Albumin

Por Sueck, Franziska, Poór, Miklós, Faisal, Zelma, Gertzen, Christoph G. W., Cramer, Benedikt, Lemli, Beáta, Kunsági-Máté, Sándor, Gohlke, Holger, Humpf, Hans-Ulrich
Publicado no Toxins (Basel) (2018)

Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication

Por Klinker, Stefan, Stindt, Sabine, Gremer, Lothar, Bode, Johannes G., Gertzen, Christoph G. W., Gohlke, Holger, Weiergräber, Oliver H., Hoffmann, Silke, Willbold, Dieter
Publicado no J Biol Chem (2019)

Design, synthesis and biological evaluation of β-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity

Por Reßing, Nina, Marquardt, Viktoria, Gertzen, Christoph G. W., Schöler, Andrea, Schramm, Alexander, Kurz, Thomas, Gohlke, Holger, Aigner, Achim, Remke, Marc, Hansen, Finn K.
Publicado no Medchemcomm (2018)

Semisynthetic Analogs of the Antibiotic Fidaxomicin—Design, Synthesis, and Biological Evaluation

Por Dorst, Andrea, Berg, Regina, Gertzen, Christoph G. W., Schäfle, Daniel, Zerbe, Katja, Gwerder, Myriam, Schnell, Simon D., Sander, Peter, Gohlke, Holger, Gademann, Karl
Publicado no ACS Med Chem Lett (2020)

Structural assemblies of the di- and oligomeric G-protein coupled receptor TGR5 in live cells: an MFIS-FRET and integrative modelling study

Por Greife, Annemarie, Felekyan, Suren, Ma, Qijun, Gertzen, Christoph G. W., Spomer, Lina, Dimura, Mykola, Peulen, Thomas O., Wöhler, Christina, Häussinger, Dieter, Gohlke, Holger, Keitel, Verena, Seidel, Claus A. M.
Publicado no Sci Rep (2016)

Synthesis, Biological Evaluation and Molecular Modeling of Substituted Indeno[1,2-b]indoles as Inhibitors of Human Protein Kinase CK2

Por Alchab, Faten, Ettouati, Laurent, Bouaziz, Zouhair, Bollacke, Andre, Delcros, Jean-Guy, Gertzen, Christoph G.W., Gohlke, Holger, Pinaud, Noël, Marchivie, Mathieu, Guillon, Jean, Fenet, Bernard, Jose, Joachim, Le Borgne, Marc
Publicado no Pharmaceuticals (Basel) (2015)

JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility

Por Lin, Minhui, Nebral, Karin, Gertzen, Christoph G. W., Ganmore, Ithamar, Haas, Oskar A., Bhatia, Sanil, Fischer, Ute, Kuhlen, Michaela, Gohlke, Holger, Izraeli, Shai, Trka, Jan, Hu, Jianda, Borkhardt, Arndt, Hauer, Julia, Auer, Franziska
Publicado no Leukemia (2019)

A promiscuous ancestral enzyme´s structure unveils protein variable regions of the highly diverse metallo-β-lactamase family

Por Perez-Garcia, Pablo, Kobus, Stefanie, Gertzen, Christoph G. W., Hoeppner, Astrid, Holzscheck, Nicholas, Strunk, Christoph Heinrich, Huber, Harald, Jaeger, Karl-Erich, Gohlke, Holger, Kovacic, Filip, Smits, Sander H. J., Streit, Wolfgang R., Chow, Jennifer
Publicado no Commun Biol (2021)