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A Membrane-proximal, C-terminal α-Helix Is Required for Plasma Membrane Localization and Function of the G Protein-coupled Receptor (GPCR) TGR5

The C terminus of G protein-coupled receptors (GPCRs) is important for G protein-coupling and activation; in addition, sorting motifs have been identified in the C termini of several GPCRs that facilitate correct trafficking from the endoplasmic reticulum to the plasma membrane. The C terminus of th...

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Detalhes bibliográficos
Main Authors: Spomer, Lina, Gertzen, Christoph G. W., Schmitz, Birte, Häussinger, Dieter, Gohlke, Holger, Keitel, Verena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916567/
https://ncbi.nlm.nih.gov/pubmed/24338481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.502344
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