Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules

Therapies to prevent transmission of malaria parasites to the mosquito vector are a vital part of the global malaria elimination agenda. Primaquine is currently the only drug with such activity; however, its use is limited by side effects. The development of transmission-blocking strategies requires...

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Detalhes bibliográficos
Main Authors: Trenholme, Katharine, Marek, Linda, Duffy, Sandra, Pradel, Gabriele, Fisher, Gillian, Hansen, Finn K., Skinner-Adams, Tina S., Butterworth, Alice, Ngwa, Che Julius, Moecking, Jonas, Goodman, Christopher D., McFadden, Geoffrey I., Sumanadasa, Subathdrage D. M., Fairlie, David P., Avery, Vicky M., Kurz, Thomas, Andrews, Katherine T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068603/
https://ncbi.nlm.nih.gov/pubmed/24733477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02721-13
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