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Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
Plasmodium falciparum parasites are responsible for the major global disease malaria, which results in >2 million deaths each year. With the rise of drug-resistant malarial parasites, novel drug targets and lead compounds are urgently required for the development of new therapeutic strategies. He...
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Main Authors: | , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2636733/ https://ncbi.nlm.nih.gov/pubmed/19196988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807398106 |
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