Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A

av Sherman, Alexandra, Biswas, Moanaro, Herzog, Roland W.
I publikationen Front Immunol (2017)

Suppression of inhibitor formation against FVIII in a murine model of hemophilia A by oral delivery of antigens bioencapsulated in plant cells

av Sherman, Alexandra, Su, Jin, Lin, Shina, Wang, Xiaomei, Herzog, Roland W., Daniell, Henry
Publicerad 2014

Oral delivery of Acid Alpha Glucosidase epitopes expressed in plant chloroplasts suppresses antibody formation in treatment of Pompe mice

av Su, Jin, Sherman, Alexandra, Doerfler, Phillip A., Byrne, Barry J., Herzog, Roland W., Daniell, Henry
I publikationen Plant Biotechnol J (2015)

Mechanism of Oral Tolerance Induction to Therapeutic Proteins

av Wang, Xiaomei, Sherman, Alexandra, Liao, Gongxian, Leong, Kam W., Daniell, Henry, Terhorst, Cox, Herzog, Roland W
Publicerad 2012

Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia...

av Kwon, Kwang‐Chul, Sherman, Alexandra, Chang, Wan‐Jung, Kamesh, Aditya, Biswas, Moanaro, Herzog, Roland W., Daniell, Henry
I publikationen Plant Biotechnol J (2017)

Combination Therapy for Inhibitor Reversal in Haemophilia A Using Monoclonal Anti-CD20 and Rapamycin

av Biswas, Moanaro, Rogers, Geoffrey L., Sherman, Alexandra, Byrne, Barry J., Markusic, David M., Jiang, Haiyan, Herzog, Roland W.
I publikationen Thromb Haemost (2016)

CTIM-04. UPDATES FOR A PHASE 2 OPEN-LABELED STUDY OF PEMBROLIZUMAB PLUS TTFIELDS PLUS MAINTENANCE TEMOZOLOMIDE IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (2-THE-TOP)

av Ghiaseddin, Ashley, Warren, Sonisha, Allen, Annie, Sampson, Deborah, Chen, Dongjiang, Sherman, Alexandra, Greene, Valerie, Rahman, Maryam, Tran, David
I publikationen Neuro Oncol (2020)

Prion Strain Discrimination Based on Rapid In Vivo Amplification and Analysis by the Cell Panel Assay

av Karapetyan, Yervand Eduard, Saá, Paula, Mahal, Sukhvir Paul, Sferrazza, Gian Franco, Sherman, Alexandra, Salès, Nicole, Weissmann, Charles, Lasmézas, Corinne Ida
Publicerad 2009

Portal Vein Delivery of Viral Vectors for Gene Therapy for Hemophilia

av Sherman, Alexandra, Schlachterman, Alexander, Cooper, Mario, Merricks, Elizabeth P., Raymer, Robin A., Bellinger, Dwight A., Herzog, Roland W., Nichols, Timothy C.
I publikationen Methods Mol Biol (2014)

Dynamics of antigen presentation to transgene product-specific CD4(+) T cells and of Treg induction upon hepatic AAV gene transfer

av Perrin, George Q, Zolotukhin, Irene, Sherman, Alexandra, Biswas, Moanaro, de Jong, Ype P, Terhorst, Cox, Davidoff, Andrew M, Herzog, Roland W
I publikationen Mol Ther Methods Clin Dev (2016)

TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer

av Butterfield, John S.S., Biswas, Moanaro, Shirley, Jamie L., Kumar, Sandeep R.P., Sherman, Alexandra, Terhorst, Cox, Ling, Chen, Herzog, Roland W.
I publikationen Hum Gene Ther Methods (2019)

Low cost industrial production of coagulation factor IX bioencapsulated in lettuce cells for oral tolerance induction in hemophilia B

av Su, Jin, Zhu, Liqing, Sherman, Alexandra, Wang, Xiaomei, Lin, Shina, Kamesh, Aditya, Norikane, Joey H., Streatfield, Stephen J., Herzog, Roland W., Daniell, Henry
I publikationen Biomaterials (2015)

Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP(+)CD4(+) T cells

av Wang, Xiaomei, Su, Jin, Sherman, Alexandra, Rogers, Geoffrey L., Liao, Gongxian, Hoffman, Brad E., Leong, Kam W., Terhorst, Cox, Daniell, Henry, Herzog, Roland W.
I publikationen Blood (2015)

Oral Tolerance Induction in Hemophilia B Dogs Fed with Transplastomic Lettuce

av Herzog, Roland W., Nichols, Timothy C., Su, Jin, Zhang, Bei, Sherman, Alexandra, Merricks, Elizabeth P., Raymer, Robin, Perrin, George Q., Häger, Mattias, Wiinberg, Bo, Daniell, Henry
I publikationen Mol Ther (2017)

Type I IFN Sensing by cDCs and CD4(+) T Cell Help Are Both Requisite for Cross-Priming of AAV Capsid-Specific CD8(+) T Cells

av Shirley, Jamie L., Keeler, Geoffrey D., Sherman, Alexandra, Zolotukhin, Irene, Markusic, David M., Hoffman, Brad E., Morel, Laurence M., Wallet, Mark A., Terhorst, Cox, Herzog, Roland W.
I publikationen Mol Ther (2020)

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8(+) T cells

av Rogers, Geoffrey L., Shirley, Jamie L., Zolotukhin, Irene, Kumar, Sandeep R. P., Sherman, Alexandra, Perrin, George Q., Hoffman, Brad E., Srivastava, Arun, Basner-Tschakarjan, Etiena, Wallet, Mark A., Terhorst, Cox, Biswas, Moanaro, Herzog, Roland W.
I publikationen Blood (2017)